Welcome to MTHFR MD a place for those with chronic illnesses related to glutathione deficiency. Glutathione plays an important role in detoxification and immune function. Understanding how the MTHFR genetic anomaly can interfere with glutathione production can be a key factor in recovery. Glutathione deficiency is found in numerous chronic illnesses including: cancer, asthma, fibromyalgia, chronic fatigue, and most neurological conditions. Knowing the glutathione status of these patients can be very helpful in designing a successful treatment plan. Unfortunately, it is rarely done.